Serum parathyroid hormone levels were elevated in 34% of patients and were in the upper half of the normal range in 43%
Hydrochlorothiazide
The mechanism for this hypercalcemic effect is not known but appears to require the presence of the parathyroid glands
Thiazide diuretics cause mild hypercalcemia
ercalcemia is associated with nausea, vomiting, abdominal pain, excessive thirst, muscle weakness, lethargy, confusion, and fatigue
Hypercalcemic crisis is a life-threatening emergency
Hypercalcemia can cause stomach upset, nausea, vomiting and constipation
Calcium reabsorption and urinary calcium excretion can be affected by the administration of diuretics
lower back or side pain
Aggressive intravenous rehydration is the mainstay of management in severe hypercal-cemia, and antiresorptive agents, such as calcitonin and Thiazide-induced hypercalcemia is mainly explained by enhanced renal proximal calcium reabsorption, changing preexistent asymptomatic normocalcemic or intermittently hypercalcemic hyperparathyroidism into the classic hypercalcemic hyperparathyroidism
Your doctor may want you to have skin examinations on a regular basis
pains
1979 Sep 8;121 (5):591-4
Severe hypercalcemia associated with hydrochlorothiazide and calcium carbonate therapy
5 mg, 25 mg Previous reports suggest that very high doses of vitamin A is required to cause hypercalcemia
Hydrochlorothiazide (diuretic pills used for high blood pressure and edema) Lithium; Vitamin A; Certain types of cancers that affect your blood, lungs, or breasts can also cause hypercalcemia
Hydrochlorothiazide causes falsely decreased values by interfering with formation of the Kober chromogen, and with the assay of Prednisone
Digestive system
4 Additional causes are listed in Hydrochlorothiazide: Reduction of urinary calcium can reduce risk of Electrolyte derangements: Hypokalemia, hyponatremia, hypomagnesemia, hypercalcemia, and hyperchloremic alkalosis may occur as a result of hydrochlorothiazide blocking the sodium chloride cotransporter in the distal convoluted tubules as described earlier
weakness
But if they become bothersome, talk with Why Do Diuretics Cause Hypercalcemia? Diuretics: Thiazide diuretics like hydrochlorothiazide (Microzide) and chlorthalidone are used to treat high blood pressure, but high calcium levels are a well-known side effect
3
Eventually, the hypercalcemia overcomes the normal parathyroid hormone effect of decreasing urinary calcium excretion, and the result is hypercalciuria (e
8 mg/dL