Metoclopramide is used to relieve heartburn and speed the healing of ulcers and sores in the esophagus (tube that connects the mouth to the stomach) in people who have
Complex pharmacology; mechanism(s) of action not fully elucidated; principal effects involve the GI tract and CNS
arrhythmias (supraventricular tachycardia, bradycardia), hypertension, hypotension
difficulty with speaking or swallowing
The ‘Musical Capital of Colombia’ Ibagué, capital of the department of Tolima, is a land so full of music that its hymn isn’t a military melody, but rather a joyful popular folklore song
Dopamine is a chemical made by your brain that affects many parts of your body, including the digestive tract
If this happens do not drive and do not use tools or machines until you feel well again
severe nervous system reaction very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out
Adult dosage (ages 18–64 years) Typical starting dosage: 10 mg taken up to four times per day
Stimulates motility of the
This medicine is also used to prevent the nausea and vomiting that may occur after surgery or after treatment with cancer medicines
7326/0003-4819-98-1-86
Metoclopramide is a benzamide (a para-aminobenzoic acid derivative) which acts as a prokinetic agent on the gastrointestinal tract and an antiemetic, particularly in persons with gastrointestinal dysmotility
1 Mechanism of Action
Administration of this drug leads to prokinetic effects which are mediated by inhibitory actions on presynaptic and postsynaptic D2 receptors, agonism
Metoclopramide - Mechanism of Action
Mechanism of Action
GI haemorrhage, mechanical obstruction or GI perforation
Known history of methemoglobinemia w/ metoclopramide or NADH cytochrome-b5 deficiency
However, clinically this action is secondary to that exerted through 5HT 4 receptors